Is mixing COVID vaccines OK? Most likely, an FDA panel says

Is mixing COVID vaccines OK? Most likely, an FDA panel says

Members of an advisory panel to the US Food and Drug Administration voted unanimously on Friday to recommend boosters for everyone who received Johnson & Johnson’s one-dose COVID-19 vaccine. Later in the meeting, members addressed the question of whether people need to stick to their original vaccine for boosters, especially in light of preliminary data that suggests mixing COVID-19 vaccines, or “heterologous priming,” is effective or even beneficial in some cases. There wasn’t a vote, and no authorization is on the table quite yet, but the question is growing increasingly loud: Do you need the same vaccine for a second (or third) coronavirus shot?

Some adults who initially received Pfizer are now eligible for a booster shot of Pfizer, including adults who are at risk of severe COVID-19 because of a health condition and folks whose jobs put them at high risk of transmission. (Immunocompromised people who received an mRNA vaccine have been eligible for a third dose of Moderna or Pfizer for a while.) Moderna’s and Johnson & Johnson’s booster doses have recently received recommendations for authorization by the FDA’s advisory committee, but are waiting on official authorization by the FDA and recommendations for use and distribution by the US Centers for Disease Control and Prevention.

But before anyone is given the stamp of approval to mix vaccines, the FDA will likely have to change the language in its emergency use authorization for the coronavirus vaccines to allow different combinations, The New York Times reported.

Mixing COVID-19 vaccines is being done in other countries, and it’s also being done unofficially in medical offices as some people seek out COVID-19 boosters for themselves. But before they make an official recommendation or give any sort of green light, scientists in the US need to determine whether the benefits of mixing different vaccine types outweigh the potential risks, and consider the differences between the vaccines…Read more>>